SK-OV-3 cells
Human SK-OV-3 cells were isolated from the ovary of patient with ovarian adenocarcinoma.
Tumour growth in vivo
The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of SCID/CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing SK-OV-3 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.
Figure 1: (View PDF)
Tumour growth curve of the SK-OV-3 cells as subcutaneous tumors Mean ± SEM (n=4; take rate 100%)