A2780 cells
Human A2780 cells were isolated from a patient with ovarian endometrioid adenocarcinoma.
Tumour growth in vivo
The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of SCID-CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing A2780 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.
Figure 1: (View PDF)
Tumour growth curve of the A2780 cells as xenograft Mean ± SEM (n=3; take rate 100%)
Standard-Of-Care Drug Responses
gemcitabine 120 mg/kg 3x/w from implantation → Response
Figure 2: (View PDF)
Effect of gemcitabine treatment on A2780 tumour growth
Mean ± SEM (n=3 per group; take rate 100%)