Tumour model

MEL-JUSO

Cutaneous melanoma
XenograftIn vitro

MEL JUSO cells

Human MEL JUSO cells were isolated from the primary tumor of a patient with melanoma.

Tumour growth in vivo

The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of SCID/CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing MEL JUSO tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.

Figure 1: (View PDF)
Tumour growth curve of the MEL JUSO cells as subcutaneous tumors Mean ± SEM (n=6; take rate 100%)

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Model characteristics

Organism
Human
Tissue of origin
Skin
Pathology
Cutaneous melanoma
Model type
In vitro, Xenograft
Availability
2 to 3 weeks

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