Tumour model

Colo 829

Melanoma
XenograftIn vitro

Colo 829 cells

Human Colo 829 cells were isolated from the skin of patient with melanoma.

Tumour growth in vivo

The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of Nude mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.

The mice bearing Colo 829 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.

Figure 1: (View PDF)
Tumour growth curve of the Colo 829 cells as subcutaneous tumors, Mean ± SEM (n=4)

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Model characteristics

Organism
Human
Tissue of origin
Skin
Pathology
Melanoma
Model type
In vitro, Xenograft
Availability
Off the shelf (time of expansion)

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