Tumour model

MIA PaCa-2

carcinoma - PDAC
XenograftIn vitro

MIA PaCa-2 cells

Human MIA PaCa-2 cells were isolated from the pancreas of a patient with pancreatic carcinoma.

Tumour growth in vivo

The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of SCID-CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing MIA PaCa-2 tumours can be treated by intra-peritoneal, intra-venous, intratumoral or subcutaneous injection of the compounds. Per os administration is also possible.

Figure 1:(View PDF)
Tumour growth curve of the MIA PaCa-2 cells as xenograft Mean ± SEM (n=2; take rate 90%)

Download PDF

Model characteristics

Organism
Human
Tissue of origin
Pancreas
Pathology
carcinoma - PDAC
Model type
In vitro, Xenograft
Availability
Off the shelf (time of expansion)

Request this model

Tell us about your compound and your endpoints. Our team confirms feasibility, timelines and study design before any commitment.

Related models

Other models sharing the same tissue of origin.

Model
Organism
Tissue of origin
Pathology
Type
Rat
Pancreas
Carcinoma, azaserine induced
SyngeneicIn vitro
Mouse
Pancreas
Adenocarcinoma
SyngeneicIn vitro
Human
Pancreas
Cystic fibrosis, Pancreatic ductal adenocarcinoma
XenograftIn vitro
Human
Pancreas
Adenocarcinoma
XenograftIn vitro
Rat
Pancreas
Neoplasia
SyngeneicIn vitro
Rat
Pancreas
Carcinoma
SyngeneicIn vitro