Tumour model

Capan-1

Adenocarcinoma
XenograftIn vitro

Capan-1 cells

Human Capan-1 cells were isolated from a pancreas of patient with adenocarcinoma.

Tumour growth in vivo

The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of SCID/CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.

The mice bearing Capan-1 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.

Figure 1:(View PDF)
Tumour growth curve of the Capan-1 cells as subcutaneous tumors Mean ± SEM (n=6)

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Model characteristics

Organism
Human
Tissue of origin
Pancreas
Pathology
Adenocarcinoma
Model type
In vitro, Xenograft
Availability
Off the shelf (time of expansion)

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