Tumour model

SNU-5

Gastric carcinoma
XenograftIn vitro

SNU-5 cells

Human SNU-5 cells were isolated from the stomach of a patient with gastric carcinoma.

Tumour growth in vivo

The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of SCID/CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing SNU-5 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.

Figure 1: (View PDF)
Tumour growth curve of the SNU-5 cells as subcutaneous tumors Mean ± SEM (n=6; take rate 100%)

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Model characteristics

Organism
Human
Tissue of origin
Stomach
Pathology
Gastric carcinoma
Model type
In vitro, Xenograft
Availability
Off the shelf (time of expansion)

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