Tumour model

Ramos

Burkitt's lymphoma
XenograftIn vitroResistant

Acquired resistance to: Rituximab

Ramos cells

Ramos is a Human B lymphocyte cell line isolated from a juvenile patient with Burkitt’s Lymphoma.

 Tumour growth in vivo

The cells were collected from a culture flask and injected subcutaneously in the right flank of SCIDCB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere. The mice bearing Ramos tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.

Figure 1 (View PDF)

Tumour growth curve of the Ramos cells as xenograft
Mean ± SEM (n=7; take rate 100%)

 

Antineo can also perform an intra-medullar implantation.

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Model characteristics

Organism
Human
Tissue of origin
B cells
Pathology
Burkitt's lymphoma
Model type
In vitro, Resistant, Xenograft
Availability
Off the shelf (time of expansion)

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