NCI-H1975 cells
Human NCI-H1975 cells were isolated from the lungs of a non-smoking female with non-small cell lung cancer.
Tumour growth in vivo
The cells were collected from a cell culture flask and 5×106 were injected subcutaneously in the right flank of SCID-CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing NCI-H1975 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.
Figure 1:(View PDF)
Tumour growth curve of the NCI-H1975 cells as subcutaneous tumors (#2025-17-03 cells were injected with Matrigel). Mean ± SEM