Myla cells
Human Myla cells were isolated from the independent proliferation of a non-malignant skin homing T
cell from a patient with myosis fungoides.
Tumour growth in vivo
The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of NSG mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing Myla tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.
Figure 1: (View PDF)
Tumour growth curve of the Myla cells as subcutaneous tumors Mean ± SEM (n=3; take rate 100%)