Tumour model

Isreco-1

Colorectal carcinoma
XenograftIn vitro

Isreco-1 cells

Human Isreco-1 cells were isolated from the colon of a patient with colorectal carcinoma.

Tumour growth in vivo

The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of SCID-CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing Isreco-1 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.

Figure 1: (View PDF)
Tumour growth curve of the Isreco-1 cells as xenograft Mean ± SEM (n=3; take rate 100%)

Antineo can also perform an intra-caecum implantation.

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Model characteristics

Organism
Human
Tissue of origin
Colon
Pathology
Colorectal carcinoma
Model type
In vitro, Xenograft
Availability
Off the shelf (time of expansion)

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