Tumour model

HCC1806

TNBC
XenograftIn vitro

HCC1806 cells

Human HCC1806 cells were isolated from the mammary gland of patient with acantholytic squamous cell carcinoma.

Tumour growth in vivo

The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of SCID/CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing HCC1806 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.

Figure 1:(View PDF)
Tumour growth curve of the HCC1806 cells as subcutaneous tumors Mean ± SEM (n=6; take rate 100%)

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Model characteristics

Organism
Human
Tissue of origin
Breast
Pathology
TNBC
Model type
In vitro, Xenograft
Availability
Off the shelf (time of expansion)

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