COLO 357 cells
Human COLO 357 cells were isolated from the celiac axis lymph nodes of a patient with metastatic pancreatic adenosquamous carcinoma.
Tumour growth in vivo
The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of SCID-CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing COLO 357 tumours can be treated by intra-peritoneal, intra-venous, intratumoral or subcutaneous injection of the compounds. Per os administration is also possible.
Figure 1:(View PDF)
Tumour growth curve of the COLO 357cells as xenograft Mean ± SEM (n=2; take rate 90%)