CAL-27 cells
Human CAL-27 cells were isolated from tissue taken from a patient with a lesion of the tongue.
Tumour growth in vivo
The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of SCID/CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing CAL-27 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.
Figure 1: ( View PDF)
Tumour growth curve of the CAL-27 cells as subcutaneous tumors, Mean ± SEM