Tumour model

AMO1

Myeloma
XenograftIn vitro

AMO1 cells

Human AMO1 cells were isolated from an ascite of a patient with a Plasmocytoma.

 Tumour growth in vivo

The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of NOG mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing AMO1 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.

Figure 1: (View PDF)
Tumour growth curve of the AMO1 cells as xenograft
Mean ± SEM (n=10; take rate 100%)

 

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Model characteristics

Organism
Human
Tissue of origin
Plasma cells
Pathology
Myeloma
Model type
In vitro, Xenograft
Availability
Off the shelf (time of expansion)

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