Tumour model

Yumm 1.7

Melanoma
SyngeneicIn vitro

 

Yumm1.7 cells 

Mouse Yumm1.7 cells were isolated from the skin of an adult mouse with melanoma. 

 Tumour growth in vivo 

The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of  C57Bl/6 mice. The resulting tumours were monitored by measuring two diameters with calipers, and  extrapolating the volume to a sphere.  

or subcutaneous injection of the compounds. Per os administration is also possible.  

The mice bearing Yumm1.7 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral

  • Figure 1: (view PDF)

Tumour growth curve of the Yumm1.7 cells as subcutaneous tumors Mean ± SEM (n=8; take rate 100%)

 

Download PFD

Model characteristics

Organism
Mouse
Tissue of origin
Skin
Pathology
Melanoma
Model type
In vitro, Syngeneic
Availability
Off the shelf (time of expansion)

Request this model

Tell us about your compound and your endpoints. Our team confirms feasibility, timelines and study design before any commitment.

Related models

Other models sharing the same tissue of origin.

Model
Organism
Tissue of origin
Pathology
Type
Human
Skin
Cutaneous melanoma
XenograftIn vitro
Human
Skin
Melanoma
XenograftIn vitro
Human
Skin
Melanoma
XenograftIn vitro
Human
Skin
Sarcoma
XenograftIn vitro
Mouse
Skin
Fibrosarcoma
SyngeneicIn vitro
Mouse
Skin
Squamous cell carcinoma
SyngeneicIn vitro