CCRF-CEM cells
Human CCRF-CEM cells were isolated from the peripheral blood of a child patient with Acute
Lymphoblastic Leukemia.
Tumour growth in vivo
The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of SCID-CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing CCRF-CEM tumours can be treated by intra-peritoneal, intra-venous, intratumoral or subcutaneous injection of the compounds. Per os administration is also possible.
Figure 1: (view PDF)
Tumour growth curve of the CCRF-CEM cells as xenograft
Mean ± SEM (n=3; take rate 100%)
Antineo can also perform an IV implantation, using hCD45 Flow Cytometry as follow-up of tumour
progression