Tumour model

Panc02

Adenocarcinoma
SyngeneicIn vitro

Panc02 cells

Mouse Panc02 is a well-established mouse pancreatic ductal adenocarcinoma (PDAC) model
developed by chemical induction with 3-methylcholanthrene (3-MCA).

Tumour growth in vivo

The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of
C57/Bl6 mice. The resulting tumours were monitored by measuring two diameters with calipers, and
extrapolating the volume to a sphere.
The mice bearing Panc02 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or
subcutaneous injection of the compounds. Per os administration is also possible.

Figure 1: (View PDF)

Tumour growth curve of the Panc02 cells as subcutaneous tumors Mean ± SEM (n=6; take rate 100%)

 

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Model characteristics

Organism
Mouse
Tissue of origin
Pancreas
Pathology
Adenocarcinoma
Model type
In vitro, Syngeneic
Availability
Off the shelf (time of expansion)

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