Tumour model

HNO97

Oral cavity squamous cells carcinoma
XenograftIn vitro

HNO97 cells

Human HNO97 cells were isolated from the mouth of a patient with H&N squamous cells carcinoma.

Tumour growth in vivo

The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of SCID-CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing HNO97 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.

Figure 1:(View PDF)
Tumour growth curve of the HNO97 cells as xenograft Mean ± SEM (n=3; take rate 100%)

 

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Model characteristics

Organism
Human
Tissue of origin
Head & Neck
Pathology
Oral cavity squamous cells carcinoma
Model type
In vitro, Xenograft
Availability
Off the shelf (time of expansion)

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